Posts Tagged ‘heart disease’
Anti-Aging Resveratrol Protects Against DNA Damage
At the School of Life Sciences at Lanzhou University, G.A. Liu and R.L. Zheng conducted research into the ability of polyphenols (groups of chemicals found in plants) to protect healthy cells against diseases like heart disease and cancer at the cellular level.
The Study
Seven polyphenols were studied, among them resveratrol.
DNA damage was induced by using hydrogen peroxide on human peripheral blood lymphocytes (PBL) which is known to cause single strand breakage in DNA. The researchers then observed the ability of the seven polyphenols to protect the cells against the damage the hydrogen peroxide was invoking on the cellular DNA.
Resveratrol Provides Significant Cell Protection
Resveratrol, as well as others of the seven tested polyphenols, had a substantial impact on inhibiting cell damage. The impact was dose-dependent as higher doses were more effective in cell protection.
Some of the polyphenols, however, failed to provide any protection. In fact, only three had any effect in protecting the cells against hydrogen peroxide damage (resveratrol, quercetin, and 7.8-dihydroxy-4-methyl coumarin), but these had a big enough impact to convince the researchers that they had discovered a possible mechanism explaining resveratrol’s outstanding track record in protecting against cancer and heart disease.
Cancer and Heart Disease Prevention Attributed to Resveratrol
In a 1999 study from the College of Medicine in the Institute of Biochemistry at the National Taiwan University in Taipei, Taiwan, researchers Jen-Hun Lin and Shu-Huei Tsai studied the cancer and heart disease prevention benefits of resveratrol, a red wine ingredient. Resveratrol may have therapeutic potential for acute coronary heart disease, cancer and other heart related health problems, such as clogged arteries.
Resveratrol’s strong antioxidant activities may have positive effects on many diseases and disorders like cancer, aging, vascular disease and various immune complex-mediated diseases. Experiments show that resveratrol has significant antioxidant activity on a molecular level as well as cancer chemopreventative abilities.
Moderate red wine drinking, thus the consumption of resveratrol, is thought to reduce the risk of heart disease by preventing blood platelets from clumping and causing a blood clot. There are many benefits to consuming resveratrol and the basic properties of this natural plant compound are anti-cancer, anti-heart disease, and anti-inflammatory. Resveratrol has been shown to suppress build up on artery walls, which can lead to clogged arteries. Resveratrol can be consumed in ways other than red wine drinking, such as resveratrol supplements in the form of tablets.